Life extension not far off (partially here now)

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Jesse
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Life extension not far off (partially here now)

Post by Jesse »

Within the next 50 years or so, research into life extension will very likely pay off (it already is, if you can afford it), between chemistry, genetic treatments, and various other methods life can already be extended by more than a decade in some cases.

There have been several discoveries in the past few years related to longevity. I will link to a few studies of supplements that can be taken now, and one therapy.

GlyNAC (Glycine and N-Acetylcysteine - Has increased mouse and rat lifespans by as much as 24%, and can help reduce cognitive impairment in the elderly, and people with brain damage.

https://blogs.bcm.edu/2022/03/08/fom-th ... n-in-mice/
https://www.mdpi.com/2072-6643/14/5/1114
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773349/

Hyperbaric oxygen treatment: Clinical trial reverses two biological processes associated with aging in human cells
https://www.sciencedaily.com/releases/2 ... 150728.htm
Hyperbaric oxygen therapy increases telomere length
https://pubmed.ncbi.nlm.nih.gov/33206062/

An experimental drug:

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals.

This one is still an experimental drug, it can't be obtained legally, nor should you try to obtain it illegally.

https://www.ucsf.edu/news/2020/12/41920 ... ithin-days

Another experimental drug: (offsets aging related conditions, at 85 your body would be in the same condition as a 65 year old today)

https://www.aarp.org/health/drugs-suppl ... aging.html


Some more reading:
https://www.pharmaceutical-technology.c ... -research/
https://www.medicaldaily.com/want-live- ... ork-421893
Last edited by Jesse on Tue Mar 29, 2022 11:06 am, edited 1 time in total.
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Konchog1
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Re: Life extension not far off (partially here now)

Post by Konchog1 »

Jesse wrote: Tue Mar 29, 2022 10:48 am GlyNAC (Glycine and N-Acetylcysteine - Has increased mouse and rat lifespans by as much as 24%, and can help reduce cognitive impairment in the elderly, and people with brain damage.

https://blogs.bcm.edu/2022/03/08/fom-th ... n-in-mice/
https://www.mdpi.com/2072-6643/14/5/1114
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773349/
Which was over the counter until last year. I don't know if you can get it now.
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Jesse
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Re: Life extension not far off (partially here now)

Post by Jesse »

Konchog1 wrote: Tue Mar 29, 2022 11:03 am
Jesse wrote: Tue Mar 29, 2022 10:48 am GlyNAC (Glycine and N-Acetylcysteine - Has increased mouse and rat lifespans by as much as 24%, and can help reduce cognitive impairment in the elderly, and people with brain damage.

https://blogs.bcm.edu/2022/03/08/fom-th ... n-in-mice/
https://www.mdpi.com/2072-6643/14/5/1114
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773349/
Which was over the counter until last year. I don't know if you can get it now.
It is, you can get it at GNC / Walmart, any pharmacy. I am grabbing both on amazon. I deal with serious memory issues so I am hoping the combination will help, if I live longer too then yay :D
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Kim O'Hara
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Re: Life extension not far off (partially here now)

Post by Kim O'Hara »

Jesse wrote: Tue Mar 29, 2022 10:48 am Within the next 50 years or so, research into life extension will very likely pay off ...
Yes. At least 15 years ago people were saying that "some people now alive may never die".
Here's a set of articles about it (if the links haven't died :tongue: ) - https://www.newscientist.com/article/mg ... irrelevant

Does it make a difference to us as Buddhists? I don't think so.
In terms of social justice, does it make things better or worse? Worse, because the over-privileged will become even more over-privileged.

:juggling:

:toilet:

:namaste:
Kim
Jesse
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Re: Life extension not far off (partially here now)

Post by Jesse »

Kim O'Hara wrote: Tue Mar 29, 2022 11:42 pm
Jesse wrote: Tue Mar 29, 2022 10:48 am Within the next 50 years or so, research into life extension will very likely pay off ...
Yes. At least 15 years ago people were saying that "some people now alive may never die".
Here's a set of articles about it (if the links haven't died :tongue: ) - https://www.newscientist.com/article/mg ... irrelevant

Does it make a difference to us as Buddhists? I don't think so.
In terms of social justice, does it make things better or worse? Worse, because the over-privileged will become even more over-privileged.

:juggling:

:toilet:

:namaste:
Kim
If they ever achieve immortality, I imagine they will come to regret it. A bit of life extension is probably a good thing. I wouldn't mind being around an extra 50 years or so. I certainty don't wish to be immortal though, the thought terrifies me.

If this technology becomes too easily used, and it might - as life extension may end up being achieved with something as simple as easy to make drugs, then we will have to start thinking about population control measures, laws and such. Current Birth rates with no natural deaths would get out of hand very quickly.

Anyway, I think it could be brought down in price to the point where anyone can access it. There's also the other extreme where it's hard to do and costly, and only the rich can afford it. My guess would be certain stuff will be exclusive to the rich, such as genetic therapies which vastly increase life-span, replacing organs with new ones grown from the patients own stem-cells, or even artificial organs that perform better than their biological ones.

Just recently they performed the first implantation of a custom grown heart (Grown in a pig and altered with the mans own DNA), he survived the surgery but died after two months. This is nearly exactly what happened with the first human to human heart transplant. They even lived for similar lengths of time. So I'm guessing organ replacements grown in pigs are not that far off.

https://abcnews.go.com/Health/wireStory ... s-83339981
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Shinjin
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Re: Life extension not far off (partially here now)

Post by Shinjin »

Interesting
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Konchog Thogme Jampa
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Re: Life extension not far off (partially here now)

Post by Konchog Thogme Jampa »

I wonder what kind of karma they’re making tampering with the natural scheme of things
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Könchok Thrinley
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Re: Life extension not far off (partially here now)

Post by Könchok Thrinley »

Konchog Thogme Jampa wrote: Wed Mar 30, 2022 1:13 pm I wonder what kind of karma they’re making tampering with the natural scheme of things
Prolonging life is as far as I know actually quite good... no? :shrug:
“Observing samaya involves to remain inseparable from the union of wisdom and compassion at all times, to sustain mindfulness, and to put into practice the guru’s instructions”. Garchen Rinpoche

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For those who do non-virtuous actions,
that becomes suffering indeed.

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Konchog Thogme Jampa
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Re: Life extension not far off (partially here now)

Post by Konchog Thogme Jampa »

Könchok Thrinley wrote: Wed Mar 30, 2022 1:23 pm
Konchog Thogme Jampa wrote: Wed Mar 30, 2022 1:13 pm I wonder what kind of karma they’re making tampering with the natural scheme of things
Prolonging life is as far as I know actually quite good... no? :shrug:
If you’re talking Secret Mantra longevity practices perfect.

But Transhumanism, Age-reversal technology, AI-Biology suffusion all that stuff that’s what I’m talking about.

But we live in *these interesting times* not a lot we can do about it

:popcorn:
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Könchok Thrinley
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Re: Life extension not far off (partially here now)

Post by Könchok Thrinley »

Konchog Thogme Jampa wrote: Wed Mar 30, 2022 1:35 pm If you’re talking Secret Mantra longevity practices perfect.

But Transhumanism, Age-reversal technology, AI-Biology suffusion all that stuff that’s what I’m talking about.

But we live in *these interesting times* not a lot we can do about it

:popcorn:
I mean sure, but also various drugs and treatments prolong life. Are those bad and negative?

Ofcourse not all those things are equal. Would I want to live as a head in a jar? No not really. But if there was a good treatment that would give me few good extra years of youthfullness and vigor? I'd think about it.

But yeah threse are some interesting times. Personally I am skeptical about these technologies, if it will increase anything then it will be inequality and it won't help you outrun the shadow of karma. In the meantime I will focus on the karma removing and merit generating technologies our teachers gave us. :sage:
“Observing samaya involves to remain inseparable from the union of wisdom and compassion at all times, to sustain mindfulness, and to put into practice the guru’s instructions”. Garchen Rinpoche

For those who do virtuous actions,
goodness is what comes to pass.
For those who do non-virtuous actions,
that becomes suffering indeed.

- Arya Sanghata Sutra
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justsit
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Re: Life extension not far off (partially here now)

Post by justsit »

Perhaps all well and good to prolong life, as long as you're healthy.
Adding an extra 10 or 20 years of sickness before death, maybe not such a great idea.
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Konchog Thogme Jampa
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Re: Life extension not far off (partially here now)

Post by Konchog Thogme Jampa »

Könchok Thrinley wrote: Wed Mar 30, 2022 5:46 pm
Konchog Thogme Jampa wrote: Wed Mar 30, 2022 1:35 pm If you’re talking Secret Mantra longevity practices perfect.

But Transhumanism, Age-reversal technology, AI-Biology suffusion all that stuff that’s what I’m talking about.

But we live in *these interesting times* not a lot we can do about it

:popcorn:
I mean sure, but also various drugs and treatments prolong life. Are those bad and negative?

Ofcourse not all those things are equal. Would I want to live as a head in a jar? No not really. But if there was a good treatment that would give me few good extra years of youthfullness and vigor? I'd think about it.

But yeah threse are some interesting times. Personally I am skeptical about these technologies, if it will increase anything then it will be inequality and it won't help you outrun the shadow of karma. In the meantime I will focus on the karma removing and merit generating technologies our teachers gave us. :sage:
I think you can restore eyesight through microchip technology I heard. So that’s a good example of these advances being used for a good cause.

Overall what will strong AI be like, have to wait and see I suppose
yinyangkoi
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Re: Life extension not far off (partially here now)

Post by yinyangkoi »

Well it's still temporary
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