The U.S. is a fairly big place and has a number of distinct geographical areas with distinct cultural differences. Where I live, the "midwest", people are generally tolerant although I do believe my career advancement potential would cease if my Buddhist practice were to become known at work.
I have also lived "in the South" and have travelled through areas of the country known as "the bible belt". In those areas, you'd be downright foolish to take up a permanent residence and let it be known you're a Buddhist (or a Hindu or a ______). Oh you'd probably be fine in some neighborhoods, even in the bible belt, but there are certainly large areas of the U.S. where vandalism or some form of hate crime would be considered socially acceptable against "one of them" despite being completely illegal.
There is a great deal of ignorance throughout the U.S. as to exactly what Buddhism means. Based on my own experience, I suspect most Americans, if they think about it at all, believe that Buddhists worship the Buddha as some sort of pagan god, believe in reincarnation, and have weird or unnatural secret rituals. The imagination is free to wander when facts are not known and that, I believe, is the best argument for doing something, anything, to help educate (NOT convert) my fellow Americans. Ignorance in this country about an issue as charged as religion can be hazardous to your health.
The birds have vanished down the sky. Now the last cloud drains away.
We sit together, the mountain and me, until only the mountain remains. Li Bai