First cases of totally drug resistant TB in India, one dead

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First cases of totally drug resistant TB in India, one dead

Postby Mr. G » Sat Jan 07, 2012 4:11 pm

This is as scary as it can get. The PD Hinduja hospital detected four people with total drug resistant (TDR) tuberculosis (TB), the first such cases in the country till November last year. In the last two months, eight others have been detected with TDR-TB.

Of the 12 patients, a 31-year-old woman from Dharavi died in November 2011. She underwent a surgery to remove one of the infected lungs before she passed away. Doctors say the condition is a result of inappropriate treatment of TB patients in private clinics. A person with TB can infect 15 people a year and cause an epidemic, according to doctors.

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Re: First cases of totally drug resistant TB in India, one dead

Postby Indrajala » Sat Jan 07, 2012 6:35 pm

I was in a hospital in India a few weeks ago where TB patients are also kept.

The quality of healthcare in India, especially public hospitals, leads to these problems no doubt.
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Re: First cases of totally drug resistant TB in India, one dead

Postby kirtu » Sat Jan 07, 2012 9:47 pm

I was amazed to find out that TB is the leading infectious disease in the world. Some 2M people die from it annually. Luckily over 90% of infections remain latent.

Here is an interesting paper presenting a new model for TB infection and progression.

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Re: First cases of totally drug resistant TB in India, one dead

Postby Malcolm » Sat Jan 07, 2012 10:16 pm

Huseng wrote:I was in a hospital in India a few weeks ago where TB patients are also kept.

The quality of healthcare in India, especially public hospitals, leads to these problems no doubt.


TB is not easy to get. You have to be malnourished, live in damp, cold conditions, and be continually exposed to it for a very long period of time. It is one of the hardest bacteria to culture.

TB is mostly a public health issue i.e. if people's living conditions are improved, their risk of contracting the disease lessens considerably. This is that reason that in the US most cases of TB are in the homeless population.
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Re: First cases of totally drug resistant TB in India, one dead

Postby Bhavana » Mon Jan 30, 2012 8:22 pm

I am a newly graduated nurse, and from my studies learned of MDR-TB (multi drug resistant strains) - simply put, improper or noncompliant use of treatment programs has led to mutations of the TB bacterium. Namdrol is right is stating that it is not an easy disease to get, especially for healthy people. The very young and very old are at higher risk, as are those with malnutrition, infection, immune dysfunction, those living in crowded conditions, and those who abuse drugs and alcohol. So yes, the average person doesn't need to worry too much. Still, when one hears of these mutant strains that are not responsive to any medication, it is very scary.
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Re: First cases of totally drug resistant TB in India, one dead

Postby palchi » Mon Jan 30, 2012 8:51 pm

The 'totally drug resistant' TB was named as such because they couldn't find a better term compared to the MDR-TB. TDR-TB did not respond to tests for 12 of the 14 by the WHO recommended drugs. Bad enough but not entirely hopeless yet...

More here: http://www.irinnews.org/report.aspx?reportid=94656
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Re: First cases of totally drug resistant TB in India, one dead

Postby Beatzen » Tue Jan 31, 2012 6:09 am

Namdrol wrote:
Huseng wrote:I was in a hospital in India a few weeks ago where TB patients are also kept.

The quality of healthcare in India, especially public hospitals, leads to these problems no doubt.


TB is not easy to get. You have to be malnourished, live in damp, cold conditions, and be continually exposed to it for a very long period of time. It is one of the hardest bacteria to culture.

TB is mostly a public health issue i.e. if people's living conditions are improved, their risk of contracting the disease lessens considerably. This is that reason that in the US most cases of TB are in the homeless population.


Wow that gives me a whole new context to listen through when I hear "Tibetans suffer from TB on a large scale" or some such thing. Or was it Tibetans living in India? Are they a relatively indigent refugee population? To say nothing of the poor Tibetans living in Tibet.
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