I really doubt this. Mahayana masters are known to abide very strictly to precepts excluding some modern zennists.
Even if you could establish that most forest dwelling yogins in Gandhara 2,000 years ago followed the vinaya very strictly, you would also have to establish that they would have considered it proscribed by the vinaya to ingest various substances in various ways. Unpack the word for "intoxicant" (whatever the Sanskrit term actually is) in the vinaya - what was that understood to encompass in that place and time?
Just to give an example, it is known that they did fire rituals in Gandhara probably well before Vajrayana emerged. We know that in later eras people burned datura in fire rituals. We know that can get a person high just by being in the vicinity. Would they have understood that as against the vinaya? Perhaps, I don't think we can make an a priori assumption that they would have.
Nowadays all the lamas frown on hallucinogens, but it is pretty clear they were part of the milieu of the formation of vajrayana. So one has to be careful extrapolating from today about hundreds and thousands of years ago. People get more conservative with time, as orthodoxies form. Almost no one today operates like a siddha from Abhayadatta 's stories - except maybe Hindu sadhus.