There is the concept of the icchantikas, who are said to be completely devoid of wholesome dharmas, and can never attain Nirvāna through their own power. However, in the Laṅkāvatāra Sūtra the Buddha states;
"Again, Mahamati said; Who, Blessed One, would never enter Nirvana?
The Blessed One replied: Knowing that all things are in Nirvana itself from the very beginning, the Bodhisattva-Icchantika would never enter Nirvana. But those Icchantikas who have forsaken all the stock of merit [finally] do. Those Icchantikas, Mahamati, who have forsaken all the stock of merit might some day be influenced by the power of the Tathagatas and be induced at any moment to foster the stock of merit. Why? Because, Mahamati, no beings are left aside by the Tathagatas. For this reason, Mahamati, it is the Bodhisattva-Icchantika who never enters into Nirvana."
The Bodhisattva-icchantika is the only one who never enters into NIrvāna, but this is not due to lacking wholesome dharmas, but due to a vow to continue liberating others!